BPC-157 vs TB-500: Research Considerations
Understanding the differences between two popular research peptides for laboratory studies
Overview
BPC-157 and TB-500 are two of the most studied peptides in research settings. While both are frequently used in laboratory applications, they have distinct molecular structures, mechanisms, and research applications. This guide compares their key characteristics for research purposes.
BPC-157
Full Name:
Body Protection Compound-157
Sequence:
15 amino acids
Molecular Formula:
C₆₂H₉₈N₁₆O₂₂
Origin:
Synthetic peptide derived from gastric juice protein
TB-500
Full Name:
Thymosin Beta-4 Fragment
Sequence:
43 amino acids
Molecular Formula:
C₂₁₂H₃₅₀N₅₆O₇₈S
Origin:
Synthetic version of naturally occurring thymosin beta-4
Research Applications
BPC-157 Research Focus
- •Gastrointestinal tissue studies
- •Vascular system research
- •Cellular protection mechanisms
- •Tissue repair pathway investigation
TB-500 Research Focus
- •Cell migration and differentiation studies
- •Actin protein interaction research
- •Angiogenesis pathway investigation
- •Wound healing mechanism studies
Key Differences for Research
Molecular Size
BPC-157 is a smaller peptide (15 amino acids) compared to TB-500 (43 amino acids), which may affect stability, solubility, and cellular uptake in research applications.
Mechanism of Action
BPC-157 research focuses on growth factor modulation and vascular effects, while TB-500 studies primarily investigate actin-binding properties and cell migration pathways.
Research Dosing
Typical research protocols use different concentration ranges for each peptide based on their molecular weights and potencies. Consult published literature for specific study parameters.
Stability
Both peptides require proper storage at -20°C or colder. BPC-157 is generally considered more stable in solution, while TB-500 may require more careful handling due to its larger size.
Research Use Only
Both BPC-157 and TB-500 are intended for laboratory research use only. They are not approved for human consumption, medical use, or any therapeutic applications. All research should be conducted by qualified researchers in appropriate laboratory settings.